1807518-67-7

Basic information

• Product Name: Bromoacetamido-PEG4-Acid
• Synonyms: Bromoacetamido-PEG4-Acid;1807518-67-7;1-Bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid;SCHEMBL932617;Bromoacetamido-PEG4-CH2CH2COOH;DTXSID601144605;SB67167;s10586;BP-22763;MS-26367;HY-141382;CS-0114544;1-Bromo-2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oicacid;3-[2-[2-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid;Propanoic acid, 3-[(14-bromo-13-oxo-3,6,9-trioxa-12-azatetradec-1-yl)oxy]-
• CAS NO: 1807518-67-7
• Molecular Formula: C13H24BrNO7
• Molecular Weight: 386.24
• Mol File: 1807518-67-7.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: Bromoacetamido-PEG4-Acid(CAS DataBase Reference)
• NIST Chemistry Reference: Bromoacetamido-PEG4-Acid(1807518-67-7)
• EPA Substance Registry System: Bromoacetamido-PEG4-Acid(1807518-67-7)

Safety Data

• Hazardous Substances Data: 1807518-67-7(Hazardous Substances Data)

Usage

Description

Bromoacetamido-PEG4-Acid is a PEG (polyethylene glycol) linker that features a bromide group and a terminal carboxylic acid. This molecule is designed to enhance solubility in aqueous environments due to the hydrophilic nature of the PEG spacer. The bromide acts as an effective leaving group, facilitating nucleophilic substitution reactions. Additionally, the terminal carboxylic acid can form stable amide bonds with primary amine groups when activated by agents such as EDC (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide) or HATU (hexafluorophosphate).

Uses

Used in Bioconjugation:
Bromoacetamido-PEG4-Acid is used as a bioconjugation agent for the covalent attachment of biomolecules to surfaces or other molecules. The expression is: Bromoacetamido-PEG4-Acid is used as a bioconjugation agent for the covalent attachment of biomolecules to surfaces or other molecules due to its ability to form stable amide bonds with primary amine groups.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Bromoacetamido-PEG4-Acid is used as a component in drug delivery systems for improving the solubility and bioavailability of therapeutic agents. The expression is: Bromoacetamido-PEG4-Acid is used in drug delivery systems for improving the solubility and bioavailability of therapeutic agents, leveraging its hydrophilic PEG spacer and reactivity with primary amine groups.
Used in Chemical Synthesis:
Bromoacetamido-PEG4-Acid is also utilized in chemical synthesis as a building block for creating various PEGylated compounds. The expression is: Bromoacetamido-PEG4-Acid is used in chemical synthesis as a building block for creating PEGylated compounds, taking advantage of its bromide group for nucleophilic substitution reactions and its terminal carboxylic acid for amide bond formation.
Used in Diagnostics:
In the diagnostics field, Bromoacetamido-PEG4-Acid can be employed for the development of PEGylated contrast agents or probes that enhance the imaging and detection of specific biological targets. The expression is: Bromoacetamido-PEG4-Acid is used in diagnostics for the development of PEGylated contrast agents or probes, capitalizing on its hydrophilic properties and reactivity to improve target detection and imaging.