Hydroxy-PEG3-NHS is a versatile chemical compound used in bioconjugation and drug delivery applications. It features a hydroxy-terminated polyethylene glycol (PEG) chain with three ethylene glycol units and a N-hydroxysuccinimidyl (NHS) ester functional group. The NHS ester group enables covalent attachment to amine groups on proteins, peptides, or other molecules, forming stable and bioactive conjugates. The hydrophilic PEG chain provides water solubility and biocompatibility, making Hydroxy-PEG3-NHS a valuable tool in the development of targeted and controlled-release drug delivery systems. Overall, Hydroxy-PEG3-NHS is an important building block for various biomedical and pharmaceutical applications.
1807518-71-3
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Basic information
- Product Name: Hydroxy-PEG3-NHS
- Synonyms: Hydroxy-PEG3-NHS
- CAS NO:1807518-71-3
- Molecular Formula: C13H21NO8
- Molecular Weight: 319.30774
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1807518-71-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 458.0±55.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.30±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 14.36±0.10(Predicted)
- CAS DataBase Reference: Hydroxy-PEG3-NHS(CAS DataBase Reference)
- NIST Chemistry Reference: Hydroxy-PEG3-NHS(1807518-71-3)
- EPA Substance Registry System: Hydroxy-PEG3-NHS(1807518-71-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1807518-71-3(Hazardous Substances Data)
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1807518-71-3 Usage
Uses
Used in Bioconjugation:Hydroxy-PEG3-NHS is used as a coupling agent for the formation of stable and bioactive conjugates between proteins, peptides, or other molecules and amine groups. The NHS ester group facilitates covalent attachment, enhancing the stability and functionality of the resulting conjugates.
Used in Drug Delivery Systems:
Hydroxy-PEG3-NHS is used as a component in the development of targeted and controlled-release drug delivery systems. The hydrophilic PEG chain improves water solubility and biocompatibility, allowing for the design of more effective drug delivery platforms.
Used in Pharmaceutical Industry:
Hydroxy-PEG3-NHS is used as a key building block in the synthesis of drug conjugates and drug delivery systems, enhancing the therapeutic efficacy and targeting capabilities of various pharmaceutical agents.
Used in Biomedical Research:
Hydroxy-PEG3-NHS is used as a versatile tool in the development of novel bioconjugates and drug delivery systems for biomedical research, enabling the exploration of new therapeutic approaches and the improvement of existing treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 1807518-71-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,1 and 8 respectively; the second part has 2 digits, 7 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1807518-71:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*1)+(3*8)+(2*7)+(1*1)=183
183 % 10 = 3
So 1807518-71-3 is a valid CAS Registry Number.
1807518-71-3Upstream product
1807518-71-3Downstream Products
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Hydroxy-PEG3-NHS
