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Methylamino-PEG2-t-butylester is a PEG-based compound featuring a methylamine group and a t-butyl ester. The hydrophilic PEG spacer enhances solubility in aqueous environments, while the methylamine group is reactive with various functional groups such as carboxylic acids and carbonyls. The t-butyl ester can be selectively deprotected under acidic conditions, making it a versatile building block for chemical modifications and conjugations.

1807521-04-5

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1807521-04-5 Usage

Uses

Used in Chemical Synthesis:
Methylamino-PEG2-t-butylester is used as a reagent for the preparation of maleimides, which are essential for thiol conjugation in various chemical and biological applications. Methylamino-PEG2-t-butylester's reactivity and PEGylation properties make it suitable for creating stable and functional conjugates.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methylamino-PEG2-t-butylester is used as a building block for the development of drug delivery systems and prodrugs. The PEGylation of therapeutic agents can improve their solubility, stability, and bioavailability, while the t-butyl ester allows for controlled release and activation under specific conditions.
Used in Bioconjugation:
Methylamino-PEG2-t-butylester is used as a linker for bioconjugation, enabling the attachment of biologically active molecules, such as peptides, proteins, or nucleic acids, to other molecules or surfaces. The PEG spacer provides a hydrophilic environment that can reduce aggregation and non-specific interactions, while the methylamine group allows for stable and site-specific conjugation.
Used in Materials Science:
In materials science, Methylamino-PEG2-t-butylester is used for the functionalization of surfaces and the creation of stimuli-responsive materials. Methylamino-PEG2-t-butylester's reactivity and PEGylation properties can be utilized to modify surfaces with specific chemical functionalities or to design materials that respond to changes in pH or other environmental factors.

Check Digit Verification of cas no

The CAS Registry Mumber 1807521-04-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,2 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1807521-04:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*2)+(3*1)+(2*0)+(1*4)=155
155 % 10 = 5
So 1807521-04-5 is a valid CAS Registry Number.

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