1807521-09-0

Usage

Uses

Used in Chemical Synthesis:
Ald-Ph-PEG2-t-butyl ester is used as a synthetic intermediate for the preparation of various complex molecules and bioconjugates. Its reactivity with aminooxy-containing molecules allows for the formation of stable oxime linkages, facilitating the attachment of different functional groups or biomolecules.
Used in Bioconjugation:
In the field of bioconjugation, Ald-Ph-PEG2-t-butyl ester is used as a crosslinking agent to connect biomolecules such as proteins, peptides, or nucleic acids. The formation of oxime bonds between the aldehyde group of Ald-Ph-PEG2-t-butyl ester and the aminooxy group of the target biomolecule enables the creation of stable and functional bioconjugates for various applications, including drug delivery, diagnostics, and therapeutics.
Used in Drug Delivery Systems:
Ald-Ph-PEG2-t-butyl ester is employed as a component in the design of drug delivery systems, particularly for the development of targeted therapies. The PEGylation of drug molecules or drug carriers using Ald-Ph-PEG2-t-butyl ester can improve their solubility, stability, and circulation time in the body, while the reactive aldehyde group allows for the attachment of targeting ligands, enhancing the specificity and efficacy of the drug delivery system.
Used in Diagnostics:
In diagnostic applications, Ald-Ph-PEG2-t-butyl ester can be used to modify imaging agents or contrast agents, enhancing their targeting ability and improving the signal-to-noise ratio in various imaging modalities, such as magnetic resonance imaging (MRI), fluorescence imaging, or positron emission tomography (PET).
Used in Material Science:
Ald-Ph-PEG2-t-butyl ester can be utilized in the development of functional materials, such as hydrogels, nanoparticles, or self-assembled structures, by taking advantage of its reactivity with aminooxy-containing molecules and the tunable properties of the PEG chain. This allows for the creation of stimuli-responsive materials or materials with specific biological functions, which can be applied in areas like tissue engineering, regenerative medicine, or biosensing.