1807530-11-5

Basic information

• Product Name: Propargyl-PEG4-methylamine
• Synonyms: Propargyl-PEG4-methylamine;Alkyne-PEG4-MEA
• CAS NO: 1807530-11-5
• Molecular Formula: C12H23NO4
• Molecular Weight: 245.31532
• Mol File: 1807530-11-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 317.1±32.0 °C(Predicted)
• Appearance: /
• Density: 1.002±0.06 g/cm3(Predicted)
• Solubility: Soluble in Water, DMSO, DMF, DCM
• PKA: 9.52±0.10(Predicted)
• CAS DataBase Reference: Propargyl-PEG4-methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: Propargyl-PEG4-methylamine(1807530-11-5)
• EPA Substance Registry System: Propargyl-PEG4-methylamine(1807530-11-5)

Safety Data

• Hazardous Substances Data: 1807530-11-5(Hazardous Substances Data)

Usage

Description

Propargyl-PEG4-methylamine is a PEG (polyethylene glycol) linker that features a propargyl group and a reactive methylamine group. This versatile molecule can participate in copper-catalyzed azide-alkyne click chemistry reactions with azide compounds, allowing for the formation of stable triazole linkages. The presence of the methylamine group enables reactivity with various functional groups, such as carboxylic acids, activated N-hydroxysuccinimide (NHS) esters, and carbonyls (ketones, aldehydes). The PEG4 spacer within the molecule enhances its hydrophilicity in aqueous environments, making it suitable for a range of applications.

Uses

Used in Bioconjugation:
Propargyl-PEG4-methylamine is used as a bioconjugation agent for attaching biomolecules to other molecules or surfaces. The expression is: Propargyl-PEG4-methylamine is used as a bioconjugation agent for attaching biomolecules to other molecules or surfaces due to its reactivity with various functional groups and its hydrophilic PEG spacer, which facilitates stable and specific conjugation in aqueous environments.
Used in Drug Delivery Systems:
Propargyl-PEG4-methylamine is used as a component in drug delivery systems for improving the solubility, stability, and bioavailability of therapeutic agents. The expression is: Propargyl-PEG4-methylamine is used in drug delivery systems for improving the solubility, stability, and bioavailability of therapeutic agents, leveraging its hydrophilic PEG spacer and reactivity with drug molecules or carriers.
Used in Chemical Synthesis:
Propargyl-PEG4-methylamine is used as an intermediate in the synthesis of various chemical compounds, including pharmaceuticals, dyes, and materials. The expression is: Propargyl-PEG4-methylamine is used as an intermediate in the synthesis of various chemical compounds, taking advantage of its reactivity with different functional groups and its PEG-based hydrophilicity for the development of new molecules with desired properties.
Used in Diagnostic Imaging:
Propargyl-PEG4-methylamine is used as a component in diagnostic imaging agents for enhancing the visibility of biological structures or processes. The expression is: Propargyl-PEG4-methylamine is used in diagnostic imaging agents for enhancing the visibility of biological structures or processes, utilizing its reactivity and hydrophilicity to improve the targeting and imaging properties of contrast agents.
Used in Material Science:
Propargyl-PEG4-methylamine is used in the development of new materials with specific properties, such as hydrogels, sensors, and coatings. The expression is: Propargyl-PEG4-methylamine is used in material science for the development of new materials with specific properties, including hydrogels, sensors, and coatings, due to its reactivity and hydrophilic nature, which can be tailored for various applications.