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Fluorescein-PEG3-(N-Boc)-Amine is a heterobiofunctional PEG linker that features a fluorescein dye and a Boc-protected amine group. This unique structure allows for the reactivation of the amine group under mild acidic conditions, enabling subsequent reactions with carboxylic acid, activated NHS ester, and carbonyl compounds such as ketones and aldehydes. The fluorescein dye, known for its fluorescent properties (494nm/521nm), serves as a valuable tracer for staining cells, tissues, biomarkers, or nanoparticles. This versatile reagent is instrumental in tagging biomolecules and nanoparticles for various applications.

1807534-77-5

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1807534-77-5 Usage

Uses

Used in Bioconjugation:
Fluorescein-PEG3-(N-Boc)-Amine is used as a heterobiofunctional PEG linker for bioconjugation purposes. Its Boc-protected amine group can be regenerated under mild acidic conditions, allowing for selective and site-specific conjugation to various biomolecules, enhancing their stability and solubility.
Used in Cellular and Tissue Staining:
In the field of cell biology, Fluorescein-PEG3-(N-Boc)-Amine is used as a fluorescent tracer for staining cells and tissues. The fluorescein dye's properties enable the visualization and tracking of cellular structures, processes, and interactions, which is crucial for research and diagnostics.
Used in Biomarker and Nanoparticle Labeling:
Fluorescein-PEG3-(N-Boc)-Amine is utilized as a labeling agent for biomarkers and nanoparticles. The reagent's ability to tag these entities allows for their detection, tracking, and analysis in various biological assays and imaging techniques, improving the sensitivity and specificity of these applications.
Used in Drug Delivery Systems:
In pharmaceutical research and development, Fluorescein-PEG3-(N-Boc)-Amine is employed as a component in drug delivery systems. Its PEGylation capabilities can improve the pharmacokinetics and biodistribution of drug molecules, while the fluorescent properties aid in monitoring drug delivery and distribution in vivo.
Used in Diagnostic Imaging:
Fluorescein-PEG3-(N-Boc)-Amine is used as a contrast agent in diagnostic imaging. The fluorescein dye's fluorescence properties can enhance the visualization of biological structures and processes, making it a valuable tool in both preclinical and clinical imaging applications.
Used in Research and Development:
In the realm of scientific research, Fluorescein-PEG3-(N-Boc)-Amine is used as a versatile reagent for the development of new assays, sensors, and analytical techniques. Its ability to tag and track biomolecules and nanoparticles contributes to the advancement of life sciences and biotechnology.

Check Digit Verification of cas no

The CAS Registry Mumber 1807534-77-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,3 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1807534-77:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*3)+(3*4)+(2*7)+(1*7)=185
185 % 10 = 5
So 1807534-77-5 is a valid CAS Registry Number.

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