Ald-Ph-PEG2-acid is a versatile small PEG reagent that features a benzaldehyde moiety and a terminal carboxylic acid group. The benzaldehyde group is reactive with hydrazide and aminooxy moieties, while the terminal carboxylic acid can form stable amide bonds with primary amines when activated by coupling agents such as EDC or HATU. This unique structure makes Ald-Ph-PEG2-acid a valuable component in various applications across different industries.
1807534-84-4
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Basic information
- Product Name: Ald--Ph-PEG2-acid
- Synonyms: Ald--Ph-PEG2-acid;DF-PEG2-COOH
- CAS NO:1807534-84-4
- Molecular Formula: C15H19NO6
- Molecular Weight: 309.31446
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1807534-84-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Soluble in Water, DMSO, DMF
- CAS DataBase Reference: Ald--Ph-PEG2-acid(CAS DataBase Reference)
- NIST Chemistry Reference: Ald--Ph-PEG2-acid(1807534-84-4)
- EPA Substance Registry System: Ald--Ph-PEG2-acid(1807534-84-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1807534-84-4(Hazardous Substances Data)
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1807534-84-4 Usage
Uses
Used in Pharmaceutical Industry:Ald-Ph-PEG2-acid is used as a pharmaceutical intermediate for the synthesis of drug conjugates and prodrugs. Its reactive benzaldehyde group allows for the attachment of drug molecules to PEG chains, enhancing the solubility, stability, and bioavailability of the resulting conjugates.
Used in Bioconjugation:
Ald-Ph-PEG2-acid is used as a bioconjugation agent for the attachment of biomolecules such as proteins, peptides, and nucleic acids to PEG chains. The stable amide bond formed with primary amines provides a reliable linkage, facilitating the development of PEGylated bioconjugates with improved properties.
Used in Material Science:
Ald-Ph-PEG2-acid is used as a building block in the synthesis of functional polymers and materials. The incorporation of PEG chains into polymer structures can impart properties such as enhanced solubility, reduced protein adsorption, and improved biocompatibility.
Used in Diagnostics:
Ald-Ph-PEG2-acid is used in the development of diagnostic agents, such as imaging probes and biosensors. The PEGylation of these agents can improve their stability, circulation time, and overall performance in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 1807534-84-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,3 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.Calculate Digit Verification of CAS Registry Number 1807534-84:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*3)+(3*4)+(2*8)+(1*4)=184
184 % 10 = 4
So 1807534-84-4 is a valid CAS Registry Number.
1807534-84-4Upstream product
1807534-84-4Downstream Products
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Ald--Ph-PEG2-acid
