Aminoxy-PEG4-acid is a PEG-based linker that features an aminooxy group and a terminal carboxylic acid. The hydrophilic PEG spacer enhances solubility in aqueous environments, while the aminooxy group is utilized for bioconjugation purposes, reacting with aldehydes to form oxime bonds or hydroxylamine linkages with the aid of a reductant. The terminal carboxylic acid is capable of forming stable amide bonds with primary amine groups in the presence of activators such as EDC or HATU. Due to the high reactivity and sensitivity of aminooxy compounds, Aminoxy-PEG4-acid is not stable as a neat compound and is recommended for immediate use within one week. It is typically sold as a 1.0M aqueous solution.
1807537-38-7
Post Buying Request-
-
Basic information
- Product Name: Aminoxy-PEG4-acid
- Synonyms: Aminoxy-PEG4-acid;Aminooxy-PEG4-acid;Aminoxy-PEG4-COOH;Aminooxy-PEG4-acid HCl salt
- CAS NO:1807537-38-7
- Molecular Formula: C11H23NO7
- Molecular Weight: 281.3
- EINECS: N/A
- Product Categories: N/A
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Soluble in Water, DMSO, DMF
- CAS DataBase Reference: Aminoxy-PEG4-acid(CAS DataBase Reference)
- NIST Chemistry Reference: Aminoxy-PEG4-acid(1807537-38-7)
- EPA Substance Registry System: Aminoxy-PEG4-acid(1807537-38-7)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1807537-38-7(Hazardous Substances Data)
1807537-38-7 Suppliers
Recommended suppliers
1807537-38-7 Usage
Uses
Used in Bioconjugation Applications:Aminoxy-PEG4-acid serves as a bioconjugation agent for attaching biomolecules to various surfaces or other molecules. Its aminooxy group reacts with aldehydes to form stable oxime bonds, facilitating the attachment process.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Aminoxy-PEG4-acid is used as a component in drug delivery systems. The terminal carboxylic acid allows for the formation of stable amide bonds with primary amine groups on drug molecules, enabling the development of targeted and controlled release drug formulations.
Used in Diagnostics and Imaging:
Aminoxy-PEG4-acid is utilized in the development of diagnostic and imaging agents. Its ability to form stable bonds with biomolecules allows for the attachment of imaging agents or markers to antibodies or other targeting molecules, enhancing the visibility and tracking of diseases within the body.
Used in Research and Development:
In research settings, Aminoxy-PEG4-acid is employed as a tool for the synthesis and modification of biologically active molecules. Its versatility in forming stable bonds with a variety of functional groups makes it a valuable asset in the development of new therapeutic agents and diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 1807537-38-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,3 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.Calculate Digit Verification of CAS Registry Number 1807537-38:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*3)+(3*7)+(2*3)+(1*8)=187
187 % 10 = 7
So 1807537-38-7 is a valid CAS Registry Number.
1807537-38-7Upstream product
1807537-38-7Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 1807537-38-7
Aminoxy-PEG4-acid
