180839-91-2Relevant academic research and scientific papers
Concise synthesis of α-alkyl α-amino acids and their incorporation into peptides via β-lactam-derived α-amino acid N-carboxy anhydrides
Palomo, Claudio,Aizpurua,Ganboa, Inaki,Odriozola, Beatriz,Urchegui, Raquel,Goerls, Helmar
, p. 1269 - 1270 (2007/10/03)
a-Hydroxy β-lactams in which C4 exists as a quaternary carbon are transformed in a single one-pot operation into α,α-dialkyl α-amino acid N-carboxy anhydrides providing a new approach to conformationally restricted peptide segments from non α-a
