180857-99-2

Upstream product

• 80-48-8 methyl p-toluene sulfonate 
• 180857-96-9 (S)-1-[4-{[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-5-((S)-1-hydroxy-ethyl)-4H-[1,2,4]triazol-3-yl]-ethanol 
• 111853-53-3 (S)-1-[4-amino-5-((S)-1-hydroxy-ethyl)-[1,2,4]-triazol-3-yl]-ethanol 
• 104-88-1 4-chlorobenzaldehyde 

Relevant academic research and scientific papers

Synthesis and highly diastereoselective alkylation of chiral N-[(S,S)-3,5-bis(1-methoxyethyl)-1,2,4-triazol-4-yl]arylimines

(S,S)-4-Amino-3,5-bis(1-hydroxyethyl)-1,2,4-triazole 2 (SAT) (from (S)-lactic acid and hydrazine hydrate) reacted with substituted benzaldehydes 6 to afford N-[(S,S)-3,5-bis(1-hydroxyethyl)-1,2,4-triazol-4-yl]arylimines 3 in excellent yield. Protection of