180869-44-7 Usage
General Description
N-(4-Formylpyrimidin-2-yl)acetamide is a chemical compound with the molecular formula C8H8N4O2. It is an amide derivative of pyrimidine and is commonly used in the synthesis of pharmaceuticals and agrochemicals. N-(4-ForMylpyriMidin-2-yl)acetaMide is known to exhibit antiviral, anti-inflammatory, and anti-tumor activities, making it a promising candidate for drug development. It is also used as a building block in organic synthesis to create various heterocyclic compounds. N-(4-Formylpyrimidin-2-yl)acetamide has the potential to be used in the treatment of various diseases and as a key intermediate in the production of pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 180869-44-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,8,6 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 180869-44:
(8*1)+(7*8)+(6*0)+(5*8)+(4*6)+(3*9)+(2*4)+(1*4)=167
167 % 10 = 7
So 180869-44-7 is a valid CAS Registry Number.
180869-44-7Relevant articles and documents
Pyrimidinylimidazole inhibitors of CSBP/P38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes
Adams, Jerry L.,Boehm, Jeffrey C.,Kassis, Shouki,Gorycki, Peter D.,Webb, Edward F.,Hall, Ralph,Sorenson, Margaret,Lee, John C.,Ayrton, Andrew,Griswold, Don E.,Gallagher, Timothy F.
, p. 3111 - 3116 (2007/10/03)
Pyrimidine analogs of the pyridinylimidazole class of CSBP/p38 kinase inhibitors were prepared in an effort to reduce the potent inhibition of hepatic cytochrome P450 observed for the pyridinyl compounds. The substitution of pyrimidin-4-yl, 2-methoxypyrimidin-4-yl, or 2- methylaminopyrimidin-4-yl for pyridin-4-yl effectively dissociates CSBP/p38 kinase from P450 inhibition for this series and furthermore achieves an increase in oral activity.
Compounds
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, (2008/06/13)
Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
