180965-60-0Relevant academic research and scientific papers
Homogeneous hydroxyethylation of phenyl-substituted alcohols
Sallay, Peter,Ahmed, Mohamed H. M.,Rusznak, Istvan,Farkas, Laszlo,Tungler, Antal
, p. 21 - 26 (2007/10/03)
Homogeneous glycol ether derivatives of phenyl group substituted alcohols (benzyl-, β-phenyl ethyl- and γ-phenyl propyl-) were synthesised by repeated Williamson synthesis starting in two cases from the halogen derivatives of the corresponding alcohols. In the case of β-phenylethanol the first homologue was prepared in the reaction of benzyl group protected ethylene chlorohydrine and β-phenyl-ethyl alcohol. The reaction product was hydrogenolysed (removing the benzyl group by hydrogenolyzis), halogenated and used to the synthesis of higher homologues as starting material.
