18102-34-6Relevant articles and documents
α-Halogenation as a Strategy to Functionalize Cyclohexa-2,4-dienones
Chittimalla, Santhosh Kumar,Koodalingam, Manikandan,Gadi, Vinod Kumar,Anaspure, Prasad
supporting information, p. 475 - 480 (2017/02/24)
A facile pyridine-mediated α-halogenation approach to functionalize cyclohexa-2,4-dienones is developed. A range of reactions, including organometallic coupling protocols, have been applied on these newly obtained halogenated cyclohexa-2,4-dienones, and the results are presented herein.
ON THE METALATION OF PHENOLIC COMPOUNDS: READY ACCESS TO HIGHLY SUBSTITUTED PHENOLS.
Costa, Antonio,Saa, Jose M.
, p. 5551 - 5554 (2007/10/02)
The direct metalation of several p-hydroxybenzylmethyl ethers has been studied.Those substrates possesing an electron-withdrawing group in a 1,3 relationship with the coordinating (-CH2OMe) group underwent regioselective metalation by the action of n-BuLi/THF.Highly substituted phenols can thus be readily prepared.