181024-40-8Relevant academic research and scientific papers
A convenient one-pot preparation of bicyclic 2-pyridones from acyl isocyanates utilizing trimethylsilylketene
Takaoka, Kiyo,Aoyama, Toyohiko,Shioiri, Takayuki
, p. 4977 - 4978 (1996)
4-Trimethylsiloxy-1,3-oxazin-6-ones, easily generated in situ from trimethylsilylketene and acyl isocyanates, smoothly react with the enamines of cycloalkanones to give bicyclic 2-pyridones.
A simple one-pot preparation of 2-pyridones from acyl isocyanates utilizing trimethylsilylketene
Takaoka, Kiyo,Aoyama, Toyohiko,Shioiri, Takayuki
, p. 4973 - 4976 (2007/10/03)
Trimethylsilylketene reacts with acyl isocyanates to give 4- trimethylsiloxy-1,3-oxazin-6, ones which smoothly undergo the Diels-Alder reaction with dimethyl acetylenedicarboxylate and methyl propiolate to furnish 2-pyridones.
