181040-42-6

Basic information

• Product Name: Benzoxazole, 6-(broMoMethyl)-
• Synonyms: Benzoxazole, 6-(broMoMethyl)-
• CAS NO: 181040-42-6
• Molecular Formula: C8H6BrNO
• Molecular Weight: 212.04334
• Mol File: 181040-42-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Benzoxazole, 6-(broMoMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoxazole, 6-(broMoMethyl)-(181040-42-6)
• EPA Substance Registry System: Benzoxazole, 6-(broMoMethyl)-(181040-42-6)

Safety Data

• Hazardous Substances Data: 181040-42-6(Hazardous Substances Data)

Usage

General Description

Benzoxazole, 6-(bromomethyl)- is a chemical compound that belongs to the benzoxazole family. It consists of a benzene ring fused to an oxazole ring, with a bromomethyl group attached to the 6-position of the oxazole ring. Benzoxazole, 6-(bromomethyl)- is often used as a building block in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It can also be used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Additionally, it has been studied for its potential biological activities and has shown promise in various medicinal applications.

Upstream product

• 10531-80-3 6-methyl-1,3-benzoxazole 

Relevant articles and documents

BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS

The present invention relates to benzoxazinone derivatives, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in treating disorders mediated by GlyT1, including neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder.

Multicyclic bis-amide MMP inhibitors

The present invention relates generally to bis-amide group containing pharmaceutical agents, and in particular, to multicyclic bis-amide MMP-13 inhibitor compounds. More particularly, the present invention provides a new class of MMP-13 inhibiting compounds, containing a pyrimidinyl bis-amide group in combination with a heterocyclic moiety, that exhibit an increased potency and solubility in relation to currently known bis-amide group containing MMP-13 inhibitors.

SUBSTITUTED PHENYL COMPOUNDS WITH A SUBSTITUENT HAVING A 1,3-BENZODIOXOLE RING

This invention is directed to compounds of formula I STR1 wherein R 1 is CN, CH 2 CN, CH=CHCN, CHO, or CH=CHCO. sub. 2 H;R 2 is aryl lower alkoxy, heteroaryl lower alkoxy, aryl lower alkylthio or heteroaryl lower alkylthio wherein each of the aryl and heteroaryl moieties is optionally substituted;R 3 is halogen;R 4 is optionally substituted aryl or optionally substituted heteroaryl;R. sup.5 is carboxy or an acid isostere; X is oxygen or sulphur; and n is zero or 1; or an N-oxide thereof, prodrug thereof solvate thereof, or pharmaceutically acceptable salt thereof, which compounds have endothelin antagonist activity. The invention is also directed to methods for preparing the compounds of formula I and their pharmaceutical use.