181058-45-7

Basic information

• Product Name: ethyl 2-(2-chlorobenzylidene)-5-(4-chlorophenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
• Synonyms: ethyl 2-(2-chlorobenzylidene)-5-(4-chlorophenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
• CAS NO: 181058-45-7
• Molecular Formula: C23H18Cl2N2O3S
• Molecular Weight: 473.37162
• Mol File: 181058-45-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2-(2-chlorobenzylidene)-5-(4-chlorophenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-chlorobenzylidene)-5-(4-chlorophenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate(181058-45-7)
• EPA Substance Registry System: ethyl 2-(2-chlorobenzylidene)-5-(4-chlorophenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate(181058-45-7)

Safety Data

• Hazardous Substances Data: 181058-45-7(Hazardous Substances Data)

Upstream product

• 2698-41-1 o-chlorobenzylidene malononitrile 
• 181058-43-5 ethyl 5-(4-chlorophenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate 
• 89-98-5 2-chloro-benzaldehyde 
• 79-11-8 chloroacetic acid 
• 154866-92-9 ethyl 6-methyl-4-(4-chlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 104-88-1 4-chlorobenzaldehyde 
• 141-97-9 ethyl acetoacetate 

Relevant articles and documents

Synthesis and radiation stability of novel thiazolopyrimidines with expected antifungal activity

A number of thiazolopyrimidines (II-VII) were prepared through interaction of 6-methyl-4(4′-chlorophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5- carboxylic acid ethyl ester (Ia) with many reagents. The antifungal activity of all prepared compounds have been determined using Dithane M-45 as a standard fungicide. Some compounds showed a high fungicidal activity equivalent to that of the standard towards Aspergillus niger and Aspergillus ochraceus. Also some biologically active compounds were subjected to gamma irradiation and the structures are stable.