181059-92-7

Basic information

• Product Name: [4-(4-Benzyloxy-phenyl)-1,1-difluoro-2-hydroxy-butyl]-phosphonic acid diethyl ester
• Synonyms: [4-(4-Benzyloxy-phenyl)-1,1-difluoro-2-hydroxy-butyl]-phosphonic acid diethyl ester
• CAS NO: 181059-92-7
• Molecular Weight: 428.413
• Mol File: 181059-92-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(4-Benzyloxy-phenyl)-1,1-difluoro-2-hydroxy-butyl]-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(4-Benzyloxy-phenyl)-1,1-difluoro-2-hydroxy-butyl]-phosphonic acid diethyl ester(181059-92-7)
• EPA Substance Registry System: [4-(4-Benzyloxy-phenyl)-1,1-difluoro-2-hydroxy-butyl]-phosphonic acid diethyl ester(181059-92-7)

Safety Data

• Hazardous Substances Data: 181059-92-7(Hazardous Substances Data)

Upstream product

• 68486-77-1 3-(4-(benzyloxy)phenyl)propanal 
• 94993-99-4 diethyl difluoromethylphosphonate lithium salt 

Downstream Products

• 181059-99-4 [4-(4-Benzyloxy-phenyl)-1,1-difluoro-2-oxo-butyl]-phosphonic acid diethyl ester 

Relevant articles and documents

A new strategy for the conversion of aldehydes into difluoromethyl ketones

A three-step sequence of reactions involving the lithium salt of diethyl difluoromethylphosphonate as a difluoromethyl carrier is shown to efficiently convert aliphatic and arylic aldehydes 2 into difluoromethyl ketones 1 via a unusual carbon-phosphorus bond scission.