18109-41-6Relevant academic research and scientific papers
ANIONIC ACTIVATION BY FLUORIDE ION IN SOLID-LIQUID SYSTEMS. SYNTHESIS OF 3 (2H)-FURANONES AND 2 (5H)-FURANONES.
Sebti, S.,Foucaud, A.
, p. 1361 - 1368 (2007/10/02)
The evolution of 2-acyloxy 2-methyl 3-oxobutanamides 1 and 2-acyloxy 3-oxo 2,3-diphenylpropanamides 13 under anionic activation by cesium fluoride was studied.The fluoride ion is an efficient base for the heterocyclization of 1 into 3 (2H)-furanones and 2 (5H)-furanones, but the hydrolysis of the ester group lowered the selectivity of the reaction.However, the cleavage of 13 into the esters 14 and the cyclization of 3-benzoyloxy 3-methyl 2-butanone into bullatenone are very selective.
