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Moretenone, also known as Moretenolone, is a synthetic steroidal compound that belongs to the class of 26,27-bisnor-D-homo-5α-cholestan-3β-ol derivatives. It is primarily used as a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), an enzyme that plays a crucial role in the regulation of glucocorticoid hormones. By inhibiting 11β-HSD1, Moretenone reduces the conversion of inactive cortisone to active cortisol, thereby modulating the levels of these hormones in the body. This action has potential therapeutic applications in the treatment of conditions such as Cushing's syndrome, metabolic syndrome, and type 2 diabetes, where dysregulation of cortisol levels is implicated. Moretenone is considered a research chemical and is not approved for clinical use, with ongoing studies exploring its safety and efficacy in various medical contexts.

1812-63-1

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1812-63-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1812-63-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,1 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1812-63:
(6*1)+(5*8)+(4*1)+(3*2)+(2*6)+(1*3)=71
71 % 10 = 1
So 1812-63-1 is a valid CAS Registry Number.

1812-63-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name moretenone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:1812-63-1 SDS

1812-63-1Relevant academic research and scientific papers

A XYLOSYLGLUCOSIDE OF XANTHOXYLIN FROM SAPIUM SEBIFERUM ROOT BARK

Kouno, Isao,Saishoji, Toshihiro,Sugiyama, Midori,Kawano, Nobusuke

, p. 790 - 791 (1983)

Besides four known compounds, a new xylosylglucoside of xanthoxylin was isolated from the root bark of Chinese tallow tree, Sapium sebiferum and identified as 2-acetyl-3,5-dimethoxyphenyl-O-β-D-xylopyranosyl-(1-6)-β-D-glucopyranoside.Key Word Index - Sapium sebiferum; Euphorbiaceae; root bark; moretenone; moretenol; xanthoxylin; sitosterol β-D-glucoside; 2-acety1-3,5-dimethoxyphenyl-O-β-D-xylopyranosyl-(1-6)-β-D-glucopyranoside; (1)H NMR; (13)C NMR.

Triterpene from Adiantum lunulactum

Mukherjee,Brahmachari,Chatterjee,Mukherjee

, p. 267 - 268 (2007/10/03)

The petrol extract of the whole plants of Adiantum lunulactum has yielded a new hopane triterpene, 3β-acetoxyl-21α-H-hop-22(29)ene.

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