181223-16-5 Usage
Chemical Properties
Brownish Yellow Solid
Uses
Different sources of media describe the Uses of 181223-16-5 differently. You can refer to the following data:
1. A potent small molecule inhibitor of spleen tyrosine kinase (Syk)
2. A potent small molecule inhibitor of spleen tyrosine kinase (Syk).
Check Digit Verification of cas no
The CAS Registry Mumber 181223-16-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,2,2 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 181223-16:
(8*1)+(7*8)+(6*1)+(5*2)+(4*2)+(3*3)+(2*1)+(1*6)=105
105 % 10 = 5
So 181223-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H13N3O3S/c18-24(22,23)11-5-6-16-13(8-11)14(17(21)20-16)7-10-9-19-15-4-2-1-3-12(10)15/h1-9,19H,(H,20,21)(H2,18,22,23)/b14-7-
181223-16-5Relevant articles and documents
Indolinone derivatives as protein kinase/phosphatase inhibitors
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, (2008/06/13)
The present invention relates to certain 2-indolinone compounds which modulate the activity of protein kinases (“PKs”) and phosphatases. The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
