181226-61-9

Basic information

• Product Name: 5H-Imidazo[1,2-a]azepine, 3-(4-chlorophenyl)-6,7,8,9-tetrahydro-
• CAS NO: 181226-61-9
• Molecular Formula: C14H15ClN2
• Molecular Weight: 246.739
• Mol File: 181226-61-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5H-Imidazo[1,2-a]azepine, 3-(4-chlorophenyl)-6,7,8,9-tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Imidazo[1,2-a]azepine, 3-(4-chlorophenyl)-6,7,8,9-tetrahydro-(181226-61-9)
• EPA Substance Registry System: 5H-Imidazo[1,2-a]azepine, 3-(4-chlorophenyl)-6,7,8,9-tetrahydro-(181226-61-9)

Safety Data

• Hazardous Substances Data: 181226-61-9(Hazardous Substances Data)

Upstream product

• 2525-16-8 O-methylcaprolactim 
• 5467-71-0 4-chlorophenacylamine hydrochloride 

Downstream Products

• 181226-74-4 4-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-5,6,7,8-tetrahydro-2a,4a-diaza-cyclopenta[cd]azulene 

Relevant articles and documents

COMPOUNDS WITH ACTIVITY AT RETINOIC ACID RECEPTORS

Disclosed herein is a compound of Formula (I) and pharmaceutical composition comprising the same. Also disclosed herein are methods of treating, or alleviating the symptoms of, a disease comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I). The disease may be selected from the group consisting of cancer, hyperproliferative disorder, inflammatory disorder, neurological disorder, neurodegenerative disorder, eye disorder, eye condition, depression, pulmonary disorders/conditions, dermatological disorders/conditions, and infertility.

2a,4a-Diazacyclopenta[c,d]azulenes

A method of preparing 5-aryl-1,2-pentamethyleneimidazoles from O-methylcaprolactim and α-amino-acetophenone hydrochlorides is described. It is shown that 1,2-tri-, -tetra-, and -pentamethyleneimidazoles and phenacyl bromide give the corresponding quaternary imidazolium salts, cyclization of which in the presence of base gives the previously unknown 5, 6, 7, 8-tetrahydro-2a,4a-diazacyclopenta[c, d]azulenes (IVa-i). 1997 Plenum Publishing Corporation.