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181262-12-4

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181262-12-4 Usage

Chemical class

Naphthyridine carboxylic acids

Explanation

Different sources of media describe the Explanation of 181262-12-4 differently. You can refer to the following data:
1. This compound belongs to a group of chemical compounds that have a naphthyridine ring structure and a carboxylic acid functional group.
2. The compound is derived from fluoroquinolone antibiotics, which are a class of broad-spectrum antibiotics known for their bactericidal activity.
3. The compound is being investigated for its potential use as an antibacterial agent, which could be useful in treating bacterial infections.
4. The compound is specifically targeting the DNA gyrase enzyme in bacteria, which is essential for bacterial DNA replication and transcription.
5. The introduction of a chloro and cyclopropyl group on the molecule's structure enhances its antimicrobial activity, making it a promising candidate for the development of new antibiotics.
6. Due to its enhanced antimicrobial activity and ability to target DNA gyrase, this compound is considered a promising candidate for the development of new antibiotics to combat drug-resistant bacterial infections.
7. As a synthetic chemical compound, it can be further modified and optimized for pharmaceutical applications, potentially leading to the development of new and effective antibiotics.

Derivative of

Fluoroquinolone antibiotics

Potential pharmaceutical applications

Antibacterial agent

Target enzyme

DNA gyrase

Structural modifications

Chloro and cyclopropyl groups

Combating drug-resistant infections

Promising candidate

Synthetic chemical compound

Potential for pharmaceutical development

Check Digit Verification of cas no

The CAS Registry Mumber 181262-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,2,6 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 181262-12:
(8*1)+(7*8)+(6*1)+(5*2)+(4*6)+(3*2)+(2*1)+(1*2)=114
114 % 10 = 4
So 181262-12-4 is a valid CAS Registry Number.

181262-12-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-chloro-1-cyclopropyl-4-oxo-1,6-naphthyridine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:181262-12-4 SDS

181262-12-4Downstream Products

181262-12-4Relevant articles and documents

NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING)

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Page/Page column 89-90; 147-148, (2020/12/30)

The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceutical composition comprising said compounds.

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