181262-51-1

Basic information

• Product Name: (3-{(2R,4S,5R)-4-(Allyloxy-diisopropylamino-phosphanyloxy)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-3H-purin-6-yl)-carbamic acid allyl ester
• Synonyms: (3-{(2R,4S,5R)-4-(Allyloxy-diisopropylamino-phosphanyloxy)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-3H-purin-6-yl)-carbamic acid allyl ester
• CAS NO: 181262-51-1
• Molecular Weight: 824.914
• Mol File: 181262-51-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-{(2R,4S,5R)-4-(Allyloxy-diisopropylamino-phosphanyloxy)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-3H-purin-6-yl)-carbamic acid allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-{(2R,4S,5R)-4-(Allyloxy-diisopropylamino-phosphanyloxy)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-3H-purin-6-yl)-carbamic acid allyl ester(181262-51-1)
• EPA Substance Registry System: (3-{(2R,4S,5R)-4-(Allyloxy-diisopropylamino-phosphanyloxy)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-3H-purin-6-yl)-carbamic acid allyl ester(181262-51-1)

Safety Data

• Hazardous Substances Data: 181262-51-1(Hazardous Substances Data)

Upstream product

• 108554-72-9 (allyloxy)bis(diisopropylamino)phosphine 
• 181262-48-6 (3-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-3H-purin-6-yl)-carbamic acid allyl ester 
• 181262-45-3 {3-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-yl]-3H-purin-6-yl}-carbamic acid allyl ester 
• 181262-42-0 3-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-yl]-3H-purin-6-ylamine 
• 181262-34-0 Thiocarbonic acid O-[(2R,3R,3aR,9aR)-2-(6-amino-purin-3-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl] ester O-phenyl ester 
• 172842-00-1 5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-3-isoadenosine 
• 181262-31-7 (2R,3R,3aS,9aR)-2-(6-Amino-purin-3-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-ol 
• 181262-36-2 3-((2R,3aS,9aR)-5,5,7,7-Tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-3H-purin-6-ylamine 
• 19046-84-5 2'-deoxy-3-isoadenosine 
• 2273-78-1 3-[beta-D-Ribofuranosyl]-adenine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 181262-56-6 allyl [N⁶-allyloxycarbonyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-3-isoadenylyl] (3'-5')-3'-O-allyloxycarbonylthymidine 
• 181262-54-4 allyl 3'-[N⁶-allyloxycarbonyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-3-isoadenosyl] 5'-(3'-O-allyloxycarbonyl)thymidyl phosphite 

Relevant articles and documents

Methodology for the synthesis of dinucleoside monophosphates containing a 2'-deoxy-3-isoadenosine unit: 3-iso-dApT and Tp(3-iso-dA)

2'-Deoxy-3-isoadenylyl(3'-5')thymidine and thymidylyl-(3'-5')-2'-deoxy- 3-isoadenosine have been synthesized by mild protection/deprotection methodology that circumvents facile N3-C1' hydrolytic cleavage of the 2'- deoxy-3-isoadenosine moiety.