181271-35-2

Upstream product

• 181271-32-9 4-bromo-1-(4-toluenesulfonyl)indole-3-carboxaldehyde 
• 87970-14-7 3-Vinyl-1,5-dioxa-spiro[5.5]undecane 
• 52488-36-5 4-bromo-1H-indole 
• 108-24-7 acetic anhydride 
• 181271-43-2 2-{(E)-2-[3-(2,2-Dimethoxy-ethyl)-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-vinyl}-propane-1,3-diol 
• 98600-34-1 4-bromo-1H-indole-3-carbaldehyde 

Downstream Products

• 181271-37-4 Acetic acid 3-acetoxy-2-[2-(toluene-4-sulfonyl)-8-(toluene-4-sulfonylamino)-8,9-dihydro-2H-2-aza-benzo[cd]azulen-7-yl]-propyl ester 
• 181271-44-3 N-[7-(2-Hydroxy-1-hydroxymethyl-ethyl)-8,9-dihydro-2H-2-aza-benzo[cd]azulen-8-yl]-4-methyl-benzenesulfonamide 
• 181271-36-3 Acetic acid (E)-2-acetoxymethyl-4-[3-(2-oxo-ethyl)-1-(toluene-4-sulfonyl)-1H-indol-4-yl]-but-3-enyl ester 

Relevant academic research and scientific papers

An attempted total synthesis of lysergic acid via an alkene/n-sulfonylimine cyclization

Lewis acid-promoted cyclization of the N-tosylimine derived from aldehyde alkene (18) affords an interesting rearranged seven-membered ring tricycle (21) rather than the expected intermediate containing the lysergic acid skeleton.