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Acetamide, 2-cyano-N-(2-fluoro-4-methylphenyl)-, also known as 2-cyano-N-(2-fluoro-4-methylphenyl)acetamide, is a chemical compound with the molecular formula C10H10FN2O. It is a derivative of acetamide, featuring a cyano group (-CN) and a 2-fluoro-4-methylphenyl group attached to the nitrogen atom. Acetamide, 2-cyano-N-(2-fluoro-4-methylphenyl)- is an organic molecule that belongs to the class of amides and is characterized by its unique structure, which includes a fluorine atom and a methyl group on the phenyl ring. It is used in various chemical and pharmaceutical applications, such as the synthesis of pharmaceuticals and agrochemicals, due to its potential to form hydrogen bonds and its reactivity with other molecules.

1813-88-3

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1813-88-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1813-88-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,1 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1813-88:
(6*1)+(5*8)+(4*1)+(3*3)+(2*8)+(1*8)=83
83 % 10 = 3
So 1813-88-3 is a valid CAS Registry Number.

1813-88-3Downstream Products

1813-88-3Relevant academic research and scientific papers

3,4-Disubstituted isothiazoles: Novel potent inhibitors of VEGF receptors 1 and 2

Kiselyov, Alexander S.,Semenova, Marina,Semenov, Victor V.

scheme or table, p. 1195 - 1198 (2009/08/07)

Novel derivatives of isothiazoles are described as potent ATP-competitive inhibitors of vascular endothelial growth factor receptors I and II (VEGFR-1/2). A number of compounds exhibited VEGFR-2 inhibitory activity comparable to that of Vatalanib in both HTRF enzymatic and cellular assays. Several derivatives featuring bulky meta-substituents in the amide portion of the molecule displayed 4- to 8-fold specificity for VEGFR-2 versus VEGFR-1. Active molecules also showed high intrinsic permeability (>30 × 10-5 cm/min) across Caco-2 cell monolayer.

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