181369-01-7

Basic information

• Product Name: (2S,3S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(3,4-dimethyl-pent-3-enyl)-2-hydroxymethyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-3-ol
• Synonyms: (2S,3S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(3,4-dimethyl-pent-3-enyl)-2-hydroxymethyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-3-ol
• CAS NO: 181369-01-7
• Molecular Weight: 698.011
• Mol File: 181369-01-7.mol

Chemical Properties

• CAS DataBase Reference: (2S,3S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(3,4-dimethyl-pent-3-enyl)-2-hydroxymethyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(3,4-dimethyl-pent-3-enyl)-2-hydroxymethyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-3-ol(181369-01-7)
• EPA Substance Registry System: (2S,3S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(3,4-dimethyl-pent-3-enyl)-2-hydroxymethyl-1-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-quinolin-3-ol(181369-01-7)

Safety Data

• Hazardous Substances Data: 181369-01-7(Hazardous Substances Data)

Upstream product

• 181368-98-9 Methanesulfonic acid (2S,3S)-3-[2-[acetyl-(toluene-4-sulfonyl)-amino]-5-(tert-butyl-diphenyl-silanyloxymethyl)-benzyl]-2-(3,4-dimethyl-pent-3-enyl)-oxiranylmethyl ester 
• 181368-97-8 N-Acetyl-N-[4-(tert-butyl-diphenyl-silanyloxymethyl)-2-((E)-6,7-dimethyl-3-trimethylsilanyloxymethyl-octa-2,6-dienyl)-phenyl]-4-methyl-benzenesulfonamide 
• 181368-96-7 N-[4-(tert-Butyl-diphenyl-silanyloxymethyl)-2-((E)-6,7-dimethyl-3-trimethylsilanyloxymethyl-octa-2,6-dienyl)-phenyl]-4-methyl-benzenesulfonamide 
• 181368-99-0 Acetic acid (S)-1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-2-(toluene-4-sulfonylamino)-benzyl]-5,6-dimethyl-2-methylene-hept-5-enyl ester 
• 181368-95-6 N-[4-(tert-Butyl-diphenyl-silanyloxymethyl)-2-((E)-3-hydroxymethyl-6,7-dimethyl-octa-2,6-dienyl)-phenyl]-4-methyl-benzenesulfonamide 
• 181368-93-4 N-[2-Allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-4-methyl-benzenesulfonamide 
• 181368-91-2 3-Allyl-4-(toluene-4-sulfonylamino)-benzoic acid ethyl ester 
• 181368-92-3 3-(2-propenyl)-4-(p-toluenesulfonyl)aminophenylmethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 119139-41-2 methyl (2E)-2-<2-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>ethylidene>-5,6-dimethyl-5-heptenoate 
• 119139-43-4 (2S,3S)-4-<2-acetyl(p-toluenesulfonyl)amino-5-(tert-butyldiphenylsilyl)oxymethylphenyl>-2-(3,4-dimethyl-3-pentenyl)-2,3-epoxy-1-butanol 
• 119139-42-3 (2E)-2-<2-<2-acetyl(p-toluenesulfonyl)amino-5-(tert-butyldiphenylsilyl)oxymethylphenyl>ethylidene>-5,6-dimethyl-5-hepten-1-ol 
• 119139-44-5 (2S)-1-<5-(tert-butyldiphenylsilyl)oxymethyl-2-(p-toluenesulfonyl)aminophenyl>-6,7-dimethyl-3-methylene-6-octen-2-ol 
• 119139-40-1 5-(tert-butyldiphenylsilyl)oxymethyl-1-(p-toluenesulfonyl)-2-indolinole 

Downstream Products

• 181369-03-9 (4aS,9aS)-9a-(3,4-dimethyl-3-pentenyl)-6-hydroxymethyl-3,3-dimethyl-9-(p-toluenesulfonyl)-9-aza-2,4-dioxa-1,2,3,4,4a,10,9,9a-octahydroanthracene 
• 181369-04-0 (4aS,9aS)-9a-(3,4-dimethyl-3-pentenyl)-3,3-dimethyl-9-(p-toluenesulfonyl)-9-aza-2,4-dioxa-1,2,3,4,4a,10,9,9a-octahydroanthracene-6-carbaldehyde 
• 181369-06-2 (4aS,9aS)-9a-(3,4-dimethyl-3-pentenyl)-3,3-dimethyl-9-(p-toluenesulfonyl)-9-aza-2,4-dioxa-1,2,3,4,4a,10,9,9a-octahydroanthracene-6-carboxylic acid 
• 181369-05-1 (4aS,9aS)-9a-(3,4-dimethyl-3-pentenyl)-6-methoxycarbonyl-3,3-dimethyl-9-(p-toluenesulfonyl)-9-aza-2,4-dioxa-1,2,3,4,4a,10,9,9a-octahydroanthracene 
• 181369-02-8 (4aS,9aS)-7-(tert-Butyl-diphenyl-silanyloxymethyl)-4a-(3,4-dimethyl-pent-3-enyl)-2,2-dimethyl-10-(toluene-4-sulfonyl)-4a,9,9a,10-tetrahydro-4H-1,3-dioxa-10-aza-anthracene 

Relevant articles and documents

Synthetic studies on virantmycin. 2. Total synthesis of unnatural (+)-virantmycin and determination of its absolute stereochemistry

The enantioselective total synthesis of (+)-virantmycin (1) has been achieved by means of the Sharpless asymmetric epoxidation of allylic alcohol 27 followed by an intramolecular epoxide opening of the exo epoxy alcohol 32 which was derived from the endo epoxy alcohol 28. The synthesis of (+)-1 has established that the absolute configuration of the natural product (-)-1 is shown to be 2R, 3R at the two chiral centers. Further, antiviral activities of the virantmycin analogs were also examined against influenza virus.