181372-18-9

Upstream product

• 181371-85-7 7-methoxy-3-(4-methoxyphenyl)-4-nitroisoquinoline-1(2H)-one 
• 108-24-7 acetic anhydride 
• 181371-89-1 4-amino-7-methoxy-3-(4-methoxyphenyl)isoquinolin-1(2H)-one 
• 181371-81-3 7-methoxy-3-(4-methoxyphenyl)isoquinolin-1(2H)-one 

Relevant academic research and scientific papers

A convenient way to dibenzo[c,h]-1,5-naphthyridines (11-aza-benzo[c] phenanthridines)

Whereas thermal cyclisation of variously substituted 2,3-diarylacrylazides easily provided a new way to 3-aryl-isoquinolones, nitration of these compounds mainly led to corresponding 3-aryl-4-nitro-isoquinolones. After reduction into 4-amino-3-aryl-isoquinolones, amidification and subsequent cyclization gave the yet unknown title compounds.