181376-12-5Relevant academic research and scientific papers
SUBSTITUTED [(PHENYLETHANOYL)AMINO] BENZAMIDES AND THE USE THEREOF IN THE TREATMENT OF INFLAMMATORY AND CARDIO-VASCULAR DISEASES
-
Page/Page column 30, (2008/06/13)
The invention relates to substituted [(phenylethanoyl)amino] benzamides and to methods for the production thereof in addition to the use thereof in the production of medicaments for the treatment of and/or prophylaxis of illnesses, particularly inflammatory diseases such as diseases of the skin, respiratory passages and cardio-vascular diseases such as arteriosclerosis and coronary heart diseases.
Activated iododerivatives for the treatment of cancer and AIDS
-
, (2008/06/13)
A series of activated iodo-benzamide derivatives are described as antineoplastic and antiviral drug compounds. The compounds generally possess a chelating group, a thiol trapping group and an activating group. The presumptive mechanism of action in preven
α,α-difluorophosphonomethyl azobenzene derivatives as photoregulated phosphoamino acid analogs. 1. Design and synthesis
Park, Seung Bum,Standaert, Robert F.
, p. 6557 - 6560 (2007/10/03)
A series of novel, photoregulated phosphoamino acid analogs based on an azobenzene core bearing an α,α-difluoromethylphosphonate as a hydrolytically stable phosphate isostere have been prepared with N-Fmoc protection for use in peptide synthesis. Classes of reagents analogous to both phosphotyrosine and phosphoserine/threonine were prepared by a common route employing a nitrosoarene/aniline condensation to form the azo linkage and the Cu(I)-promoted coupling of an iodoarene with (diethylphosphono)difluoromethyl cadmium bromide (Burton's method) to introduce the phosphonate moiety.
Synergistic compositions useful as anti-tumor agents
-
, (2008/06/13)
The subject invention provides for novel synergistic compositions useful for inactivating viruses or inducing apoptosis in tumor cells and for treating cancer or retroviral infections. Generally, the compositions comprise one or a plurality of ligands tha
