181479-34-5Relevant academic research and scientific papers
Ether, carbonate and urethane deoxynucleoside derivatives as prodrugs
Hammer, Kristin,Hatlelid, Jostein,Grotli, Morten,Arukwe, Joseph,Klaveness, Jo,Rise, Frode,Undheim, Kjell
, p. 609 - 622 (2007/10/03)
3′-Deoxythymidine and its 3′-azido derivative, 2′,3′-dideoxycytidine, 2′,3′-dideoxyinosine and 2′,3′-dideoxyadenosine have been acylated to form carbonates and urethanes in chemoselective reactions. The nucleosides have been N- and/or O-alkylated by α-chl
