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18174-72-6

18174-72-6

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18174-72-6 Usage

Description

Muscimol HBr (18174-72-6) is a GABA-A receptor agonist.

Chemical Properties

Tan Solid

Uses

A potent but toxic structural analogue of g-aminobutyric acid (GABA), with a zwitterionic structure that can cross the blood-brain barrier.

Biochem/physiol Actions

Muscimol hydrobromide is a GABAA receptor agonist.

References

1) Akhondzadeh et al. (1995), Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors; Br. J. Pharmacol., 115 527

Check Digit Verification of cas no

The CAS Registry Mumber 18174-72-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,1,7 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18174-72:
(7*1)+(6*8)+(5*1)+(4*7)+(3*4)+(2*7)+(1*2)=116
116 % 10 = 6
So 18174-72-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2O2.BrH/c5-2-3-1-4(7)6-8-3;/h1H,2,5H2,(H,6,7);1H

18174-72-6 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Sigma

  • (G019)  Muscimol hydrobromide  ≥98% (HPLC), solid

  • 18174-72-6

  • G019-5MG

  • 1,193.40CNY

  • Detail

  • Sigma

  • (G019)  Muscimol hydrobromide  ≥98% (HPLC), solid

  • 18174-72-6

  • G019-10MG

  • 2,073.24CNY

  • Detail

  • Sigma

  • (G019)  Muscimol hydrobromide  ≥98% (HPLC), solid

  • 18174-72-6

  • G019-25MG

  • 4,126.59CNY

  • Detail

  • Sigma

  • (G019)  Muscimol hydrobromide  ≥98% (HPLC), solid

  • 18174-72-6

  • G019-100MG

  • 13,689.00CNY

  • Detail

18174-72-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(aminomethyl)-1,2-oxazol-3-one,hydrobromide

1.2 Other means of identification

Product number -
Other names Muscimol hydrobromide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18174-72-6 SDS

18174-72-6Upstream product

18174-72-6Downstream Products

18174-72-6Relevant articles and documents

4,5-Substituted 3-Isoxazolols with Insecticidal Activity Act as Competitive Antagonists of Housefly GABA Receptors

Liu, Genyan,Ozoe, Fumiyo,Furuta, Kenjiro,Ozoe, Yoshihisa

, p. 6304 - 6312 (2015/08/03)

The insect GABA receptor (GABAR), which is composed of five RDL subunits, represents an important target for insecticides. A series of 4,5-disubstituted 3-isoxazolols, including muscimol analogues, were synthesized and examined for their activities agains

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