18175-59-2

Upstream product

• 86733-15-5 (7S,8S,10R)-8-Ethyl-6,7,8,10-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione 
• 79191-09-6 C₁₁H₁₀O₄ 
• 86733-12-2 ((5S,6S,8R)-3-Bromo-6-ethyl-4,4-dimethoxy-5,6,8-tris-methoxymethoxy-1,4,5,6,7,8-hexahydro-naphthalen-1-yloxy)-tert-butyl-dimethyl-silane 
• 95385-22-1 (7S,8S,10R)-8-Ethyl-7,8,10-trihydroxy-1,6-dimethoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione 
• 86733-11-1 (7S,8S,10R)-8-Ethyl-1,7,8,10-tetrahydroxy-6-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione 

Relevant academic research and scientific papers

The synthesis of (±) α-citromycinone via a 1,4-dipole-metallated p-quinol strategy

The synthesis of the compound having the structure assigned to α-citromycinone has been completed in 4% overall yield from 2-ethyl-5,8-dimethoxy-7-bromo-1-tetralone.

THE SYNTHESIS OF 6-DEOXYANTHRACYCLINONES:(+/-)α-CITROMYCINONE AND (+/-)4-DEMETHOXY-6-DEOXYDAUNOMYCINONE

Two synthetic approaches have been explored to prepare 6-deoxyanthracyclinones in general and α-citromycinone in particular.The first approach employed as starting materials 1,4,5-trimethoxynaphthalene and the Diels-Alder product from butadiene and maleic