181764-85-2Relevant academic research and scientific papers
N-heterocyclic carbene-palladium(II)-1-methylimidazole complex catalyzed α-arylation reactions of tetralones with aryl chlorides and further transformation of the products
Yin, Hui-Ying,Lin, Xia-Li,Li, Shu-Wan,Shao, Li-Xiong
, p. 9012 - 9021 (2015)
NHC-Pd(II)-Im complex 1 has proven to be an efficient catalyst in the reaction between tetralones 2 and aryl chlorides 3, giving the α-arylated tetralones 4 in good to high yields. In addition, if the above reaction mixture was exposed to air at room temp
2-aryl-3-aminoaryloxynaphthy1 compounds, intermediates, compositions and methods
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, (2008/06/13)
The present invention provides a compound of formula I: STR1 or a pharmaceutically acceptable salt or solvate thereof; having activity as a selective estrogen receptor modulator, pharmaceutical compositions containing a compound of formula I, and methods
Naphthyl compounds and compositions, as estrogen receptor binding agents
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, (2008/06/13)
The invention provides a compound of formula I: STR1 or a pharmaceutically acceptable salt or solvate thereof; pharmaceutical compositions containing a compound of formula I, and methods of using a compound of formula I for inhibiting bone loss or bone resorption, particularly osteoporosis, and cardiovascular-related pathological conditions including hyperlipidemia, and estrogen dependent cancer.
1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods
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, (2008/06/13)
The present invention provides a class of compounds having the structure or a pharmaceutically acceptable salt where R1is hydrogen, hydroxy, alkoxy, alkoxycarbonyl, alkoxycarbonyloxy, aryloxycarbonyl, phenoxycarbonyloxy, or alkylsulfonyloxy; R
Naphthyl compounds, compositions, and methods
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, (2008/06/13)
The invention provides naphthyl compounds, formulations, and methods of inhibiting bone loss or bone resorption, particularly osteoporosis, and cardiovascular-related pathological conditions including hyperlipidemia, and estrogen-dependent cancer.
2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods
-
, (2008/06/13)
The present invention provides pharmaceutically active compounds formula I or a pharmaceutically acceptable salt or solvate thereof having activity as selective estrogen receptor modulators, pharmaceutical compositions containing the compounds, an
