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25-Anhydrocimigenol 3-O-beta-D-xyloside is a triterpenoid compound derived from the roots of Cimicifuga foetida, a perennial herb native to eastern Asia. It has been extensively studied for its potential pharmacological properties, including anti-inflammatory, anti-cancer, neuroprotective, bone health, and osteoporosis effects. Additionally, it exhibits antioxidant and anti-aging properties, making it a promising candidate for the development of new drugs for various diseases and conditions.

181765-11-7

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181765-11-7 Usage

Uses

Used in Pharmaceutical Industry:
25-Anhydrocimigenol 3-O-beta-D-xyloside is used as a pharmaceutical agent for its anti-inflammatory properties, which can help in the treatment of various inflammatory conditions.
25-Anhydrocimigenol 3-O-beta-D-xyloside is used as an anti-cancer agent for its potential to inhibit the growth and progression of cancer cells, making it a valuable component in the development of new cancer therapies.
Used in Neuroprotective Applications:
25-Anhydrocimigenol 3-O-beta-D-xyloside is used as a neuroprotective agent to protect the nervous system and prevent neurodegenerative diseases due to its neuroprotective activities.
Used in Bone Health and Osteoporosis Treatment:
25-Anhydrocimigenol 3-O-beta-D-xyloside is used as a bone health supplement and osteoporosis treatment to improve bone density and strength, reducing the risk of fractures and other bone-related issues.
Used in Antioxidant and Anti-aging Products:
25-Anhydrocimigenol 3-O-beta-D-xyloside is used as an antioxidant and anti-aging ingredient in cosmetic and skincare products to protect the skin from oxidative stress and promote a youthful appearance.

Check Digit Verification of cas no

The CAS Registry Mumber 181765-11-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,7,6 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 181765-11:
(8*1)+(7*8)+(6*1)+(5*7)+(4*6)+(3*5)+(2*1)+(1*1)=147
147 % 10 = 7
So 181765-11-7 is a valid CAS Registry Number.

181765-11-7Downstream Products

181765-11-7Relevant academic research and scientific papers

Four new 9,19-cyclolanostane derivatives from the rhizomes of Cimicifuga yunnanensis hsiao

Nian, Yin,Chen, Jian-Chao,Lu, Lu,Zhang, Xian-Ming,Zhou, Lin,Qiu, Ming-Hua

, p. 112 - 120 (2009)

Four new 9,19-cyclolanostane-type triterpenes, 24-O-acetyl-25- anhydroshengmanol-3-O-β-d-xylopyranoside (1), 25-i-butylcimigenol-3-O- β-d-xylopyranoside (2), 12-β-hydrocimigenol-3-one (3), and 12-β-hydrocimigenol-1-en-3-one (4), together with 15 known ana

Cycloartane triterpenoids from the aerial parts of Cimicifuga foetida Linnaeus

Nian, Yin,Zhang, Xian-Min,Li, Yan,Wang, Yuan-Yuan,Chen, Jian-Chao,Lu, Lu,Zhou, Lin,Qiu, Ming-Hua

experimental part, p. 1473 - 1481 (2012/01/05)

Cycloartane triterpenoids, 2′,24-O-diacetylisodahurinol-3-O-α- l-arabinopyranoside, 24-O-acetylisodahurinol-3-O-α-l-arabinopyranoside, 12β-hydroxy-25-anhydrocimigenol, cimigenol-12-one, 12β-hydroxy-15- deoxycimigenol, 2′-O-acetyl-24-epi-cimigenol-3-O-α-l- arabinopyranoside, 2′-O-acetylcimigenol-3-O-β-d-xylopyranoside, 25-anhydrocimigenol-3-O-α-l-arabinopyranoside, 2′,23-O- diacetylshengmanol-3-O-α-l-arabinopyranoside, and 2′,24-O-diacetyl- 25-anhydrohydroshengmanol-3-O-α-l-arabinopyranoside, together with eight known compounds, were isolated from aerial parts of Cimicifuga foetida. Their structures were determined by application of spectroscopic analyses and chemical methods. Biological evaluation of the compounds against human HL-60, SMMC-7721, A549, SK-BR-3, and PANC-1 cell lines indicated that three of these compounds exhibited broad-spectrum and moderate cytotoxic activities, with IC50 values ranging from 6.20 to 22.74 μM. By comparing previous cytotoxic testing data and bioassay results from this study, preliminary structure-activity relationships of compounds with a cimigenol-skeleton can be proposed.

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