181783-52-8

Basic information

• Product Name: (2R,3S,6S)-1-aza-3-methyl-6-phenyl-8-oxa-4,7-dioxobicyclo[4.3.0]nonane
• Synonyms: (2R,3S,6S)-1-aza-3-methyl-6-phenyl-8-oxa-4,7-dioxobicyclo[4.3.0]nonane
• CAS NO: 181783-52-8
• Molecular Weight: 245.278
• Mol File: 181783-52-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S,6S)-1-aza-3-methyl-6-phenyl-8-oxa-4,7-dioxobicyclo[4.3.0]nonane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,6S)-1-aza-3-methyl-6-phenyl-8-oxa-4,7-dioxobicyclo[4.3.0]nonane(181783-52-8)
• EPA Substance Registry System: (2R,3S,6S)-1-aza-3-methyl-6-phenyl-8-oxa-4,7-dioxobicyclo[4.3.0]nonane(181783-52-8)

Safety Data

• Hazardous Substances Data: 181783-52-8(Hazardous Substances Data)

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 181783-40-4 (-)-(2R,3S,6S)-2-hydroxymethyl-3-methyl-6-phenyl-4-piperidone 
• 64700-46-5 3-methyl-5-[(trimethylsilyl)oxy]-3-penten-1-yne 
• 121693-79-6 (E)-tert-butyldimethyl-((3-methylpent-2-en-4-yn-1-yl)oxy)silane 
• 154169-95-6 (S)-2-Methoxymethyl-1-((E)-2-methyl-1-methylene-4-trimethylsilanyloxy-but-2-enyl)-pyrrolidine 
• 181528-69-8 (S)-1-[(E)-4-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-1-methylene-but-2-enyl]-2-methoxymethyl-pyrrolidine 
• 181528-77-8 (2R,3S,6S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-methyl-6-phenyl-piperidin-4-one 
• 181783-49-3 (2R,3R,6S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-methyl-6-phenyl-piperidin-4-one 

Downstream Products

• 181783-53-9 (2R,3S,4R,6S)-1-aza-4-hydroxy-3-methyl-6-phenyl-8-oxa-7-oxobicyclo[4.3.0]nonane 

Relevant articles and documents

Enantioselective Synthesis of HIghly Functionalized 4-PIperidones by the Asymmetric Imino-Diels-Alder Reaction of Chiral 2-Amino-1,3-butadienes

Chiral 2-amino-1,3-butadienes 1 derived from commercially available (S)-2-methoxymethylpyrrolidine react with aromatic N-trimethylsilyaldimines and N-phenylaldimines in the presence of ZnCl2 to give, after reaction workup, 4-piperidones 4 and 6, respectively, with moderate to very high enantiomeric excesses.In addition, the absolute configurations of derivatives of 4a and 4g were determined by circular dichroism and NMR spectroscopy on the Mosher ester, respectively. - Keywords: asymmetric Diels-Alder reactions; butadienes; Diels-Alder reactions; piperidones