181797-15-9

Upstream product

• 181797-14-8 1-benzoyl-2-debenzoyl-2-(tetrahydropyran-2-yl)-4-deacetyl-7-deoxy-10-deacetyl-9,10-O-(propane-2,2-diyl)-9(R)-dihydrobaccatin III 
• 181797-12-6 C₂₈H₄₂O₈ 
• 14550-93-7 5-O-cinnamoyl-9,10-isopropylidenetaxicine I 
• 181797-07-9 C₄₀H₆₈O₁₂SSi 
• 181797-04-6 1,2-di(tetrahydropyran-2-yl)-9,10-O-(propane-2,2-diyl)-5α-cinnamoyltaxicin-I 
• 181797-27-3 C₃₄H₅₄O₁₂S 
• 181797-22-8 C₃₉H₆₆O₁₀Si 
• 181797-13-7 C₃₅H₄₆O₉ 
• 181797-06-8 C₃₃H₅₂O₁₀ 
• 181797-08-0 C₃₃H₅₀O₉ 
• 181797-05-7 C₃₃H₅₀O₈ 

Relevant academic research and scientific papers

Semisynthesis of some 7-deoxypaclitaxel analogs from taxine B

Taxine B (3), isolated from the dried needles of Taxus baccata, was converted into six novel 7-deoxypaclitaxel analogs, 20, 21a,b, and 23-25, that have structural changes at C1, C2, and C4. A method for the introduction of the benzoyl function at C2, via a benzylidene acetal at C1-C2, will be revealed. All compounds showed very little or no measurable cytotoxic activity against some well-characterized human tumor cell lines, probably due to the nonacylated hydroxyl group at C4.