Fmoc-PEG6-NHS ester is a PEG (polyethylene glycol) linker that features an Fmoc-protected amine and an NHS (N-hydroxysuccinimide) ester. This molecule is designed to enhance solubility in aqueous environments due to the hydrophilic PEG spacer. The Fmoc group can be removed under basic conditions, revealing the free amine for subsequent conjugations. The NHS ester functionality allows for the labeling of primary amines (-NH2) present in proteins, amine-modified oligonucleotides, and other amine-containing molecules.
1818294-31-3
Post Buying Request-
-
Basic information
- Product Name: Fmoc-PEG6-NHS ester
- Synonyms: Fmoc-PEG6-NHS ester
- CAS NO:1818294-31-3
- Molecular Formula: C34H44N2O12
- Molecular Weight: 672.71936
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1818294-31-3.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: Soluble in DMSO, DCM, DMF
- CAS DataBase Reference: Fmoc-PEG6-NHS ester(CAS DataBase Reference)
- NIST Chemistry Reference: Fmoc-PEG6-NHS ester(1818294-31-3)
- EPA Substance Registry System: Fmoc-PEG6-NHS ester(1818294-31-3)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1818294-31-3(Hazardous Substances Data)
1818294-31-3 Suppliers
Recommended suppliers
1818294-31-3 Usage
Uses
Used in Bioconjugation:Fmoc-PEG6-NHS ester is used as a bioconjugation agent for the modification of proteins and other amine-containing molecules. The expression is: Fmoc-PEG6-NHS ester is used as a bioconjugation agent for the modification of primary amines (-NH2) in proteins and other amine-containing molecules to enhance their solubility, stability, and bioavailability.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Fmoc-PEG6-NHS ester is used as a component in the development of drug delivery systems. The expression is: Fmoc-PEG6-NHS ester is used as a component in drug delivery systems for the conjugation of therapeutic molecules to PEG linkers, which can improve the pharmacokinetic properties and reduce the immunogenicity of the drug.
Used in Diagnostics:
Fmoc-PEG6-NHS ester is also utilized in the diagnostics industry for the labeling of oligonucleotides and other molecular probes. The expression is: Fmoc-PEG6-NHS ester is used as a labeling agent for amine-modified oligonucleotides and molecular probes to enhance their detection and functionality in diagnostic assays.
Used in Research and Development:
In the research and development sector, Fmoc-PEG6-NHS ester serves as a valuable tool for the synthesis and modification of various biomolecules. The expression is: Fmoc-PEG6-NHS ester is used as a synthetic tool for the modification and conjugation of biomolecules in research and development, facilitating the study of their structure, function, and interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1818294-31-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,1,8,2,9 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1818294-31:
(9*1)+(8*8)+(7*1)+(6*8)+(5*2)+(4*9)+(3*4)+(2*3)+(1*1)=193
193 % 10 = 3
So 1818294-31-3 is a valid CAS Registry Number.
1818294-31-3Upstream product
1818294-31-3Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 1818294-31-3
Fmoc-PEG6-NHS ester
