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Fluorescein-PEG6-NHS ester is a fluorescein-labeled PEG (polyethylene glycol) linker that features an NHS (N-hydroxysuccinimide) group. This allows for the labeling of antibodies and other purified proteins at their primary amines, which are the lysine side chains. The hydrophilic PEG spacer arm enhances solubility in aqueous media, making it a versatile tool for various applications.

1818294-35-7

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1818294-35-7 Usage

Uses

Used in Biomedical Research:
Fluorescein-PEG6-NHS ester is used as a labeling agent for antibodies and other purified proteins to enable fluorescence detection and tracking. The application reason is that the fluorescein label provides a visual marker for these biomolecules, allowing researchers to monitor their behavior, distribution, and interactions within biological systems.
Used in Drug Development:
Fluorescein-PEG6-NHS ester is used as a modification agent for therapeutic proteins to improve their pharmacokinetic properties. The application reason is that the PEGylation process, which involves the attachment of PEG molecules, can increase the solubility, stability, and circulation time of proteins in the body, potentially enhancing their therapeutic efficacy.
Used in Diagnostics:
Fluorescein-PEG6-NHS ester is used as a component in the development of diagnostic tools, such as immunoassays and fluorescence-based detection systems. The application reason is that the fluorescent label allows for sensitive and specific detection of target molecules, which can be crucial for accurate diagnosis of various conditions.
Used in Cell Biology:
Fluorescein-PEG6-NHS ester is used as a cell labeling agent to study cell surface proteins and other biomolecules. The application reason is that the fluorescent label enables the visualization and tracking of these molecules within living cells, providing insights into cellular processes and functions.
Used in Material Science:
Fluorescein-PEG6-NHS ester is used as a component in the development of biocompatible materials and coatings. The application reason is that the hydrophilic PEG spacer arm can improve the biocompatibility and non-fouling properties of these materials, making them suitable for various applications in the medical and biotechnology fields.

Check Digit Verification of cas no

The CAS Registry Mumber 1818294-35-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,1,8,2,9 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1818294-35:
(9*1)+(8*8)+(7*1)+(6*8)+(5*2)+(4*9)+(3*4)+(2*3)+(1*5)=197
197 % 10 = 7
So 1818294-35-7 is a valid CAS Registry Number.

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