181872-61-7

Basic information

• Product Name: Isoquinoline, 4-methoxy-1-methyl- (9CI)
• Synonyms: Isoquinoline, 4-methoxy-1-methyl- (9CI)
• CAS NO: 181872-61-7
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 173.21114
• Product Categories: METHOXY
• Mol File: 181872-61-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isoquinoline, 4-methoxy-1-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline, 4-methoxy-1-methyl- (9CI)(181872-61-7)
• EPA Substance Registry System: Isoquinoline, 4-methoxy-1-methyl- (9CI)(181872-61-7)

Safety Data

• Hazardous Substances Data: 181872-61-7(Hazardous Substances Data)

Upstream product

• 1374461-37-6 N-methoxy 1-methylisoquinolinium perchlorate 

Relevant articles and documents

Regioselective photochemical C-OMe bond formation initiated by one-electron transfer and N-OMe bond fragmentation in electron donor-acceptor systems

Compounds that integrate electron donor-acceptor subunits with N-methoxyisoquinolinium as acceptors and substituted (methoxy)benzenes as donors were synthesized and their luminescent and photochemical properties studied. Photolysis yielded the corresponding photomethoxylation products in a two-step process that involves N-OMe bond scission followed by C-OMe bond formation. Homolysis of the N-OMe bond restores the aromatic isoquinoline nucleus and produces a methoxy radical that can couple to the required ring carbon atom in the benzene cation radical to give the products in a regioselective process controlled by the spin density of the cation radical. This photoprocess involves two different pathways: methoxylation of the acceptor (intracomponent methoxylation) or the donor (intercomponent metoxylation). Both methoxy-transfer pathways are controlled by the donoating ability (redox potential) of the donor subunit, consistent with the emission observed upon excitation of the charge-transfer state in systems that undergo intermethoxylation.