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1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one, with the molecular formula C10H11IO3Si, is a highly reactive and versatile reagent in organic synthesis. It serves as a source of electrophilic iodine and is renowned for its ability to act as an iodine(III) source in a variety of reactions, such as oxidative transformations and C-H bond functionalization. Its unique structure and reactivity make it an indispensable tool in synthetic chemistry for the efficient and selective formation of carbon-carbon and carbon-heteroatom bonds, as well as in the preparation of complex natural products and pharmaceuticals. However, due to its potential toxicity and the reactivity of the iodine center, it should be handled and used with caution.

181934-29-2

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181934-29-2 Usage

Uses

Used in Organic Synthesis:
1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one is used as a reagent for oxidative transformations and C-H bond functionalization in organic synthesis. Its role as an electrophilic iodine source facilitates the formation of carbon-carbon and carbon-heteroatom bonds, which is crucial for the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its ability to participate in selective bond formations contributes to the development of new drugs with improved efficacy and reduced side effects.
Used in Natural Product Synthesis:
1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one is employed as a reagent in the synthesis of complex natural products. Its unique reactivity aids in the construction of intricate molecular frameworks that are often found in bioactive natural compounds.
Used in Research and Development:
In research and development, 1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one is used as a tool to explore new reaction mechanisms and to develop innovative synthetic methodologies. Its versatility and reactivity provide researchers with a means to investigate novel chemical transformations and to expand the scope of synthetic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 181934-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,9,3 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 181934-29:
(8*1)+(7*8)+(6*1)+(5*9)+(4*3)+(3*4)+(2*2)+(1*9)=152
152 % 10 = 2
So 181934-29-2 is a valid CAS Registry Number.

181934-29-2 Well-known Company Product Price

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  • (Code)Product description
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  • TCI America

  • (T3272)  1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one  >98.0%(T)

  • 181934-29-2

  • 1g

  • 1,100.00CNY

  • Detail
  • TCI America

  • (T3272)  1-[(Trimethylsilyl)ethynyl]-1,2-benziodoxol-3(1H)-one  >98.0%(T)

  • 181934-29-2

  • 5g

  • 4,750.00CNY

  • Detail

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