18196-29-7Relevant academic research and scientific papers
NOVEL (-)-ENANTIOMERS OF CIS-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
-
, (2008/06/13)
The present invention relates to therapeutically active compounds of formula (I), a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related
Synthesis and pharmacological evaluation of novel cis-3,4-Diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor
Bury, Paul S.,Christiansen, Lise B.,Jacobsen, Poul,Jorgensen, Anker S.,Kanstrup, Anders,Narum, Lars,Bain, Steven,Fledelius, Christian,Gissel, Birgitte,Hansen, Birgit S.,Korsgaard, Niels,Thorpe, Susan M.,Wassermann, Karsten
, p. 125 - 145 (2007/10/03)
The syntheses and in vitro pharmacological evaluation of a number of cis-3,4-diaryl-hydroxy-chromanes are reported, along with the results of a thorough in vivo profiling of the tissue-selective estrogen partial-agonist NNC 45-0781 [3, (-)-(3S,4R)-7-hydro
cis3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
-
, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
-
, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
-
, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I STR1 a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen relat
(+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes
-
, (2008/06/13)
The present invention relates to therapeutically active compounds of formula I a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related di
