18203-85-5Relevant articles and documents
Effect of Alkyl Substituents on the Thermodynamics of the Self-association of Purine in Aqueous Solution
Loennberg, Harri,Ylikoski, Jyrki,Vesala, Antti
, p. 2439 - 2444 (1984)
The thermodynamic parameters for the self-association of several alkyl-substituted purines have been determined by applying the isodesmic model to the molar enthalpies of infinite dilution at different initial concentrations.Carbon-bonded alkyl groups have been shown to increase the tendency to association by making the association enthalpy more negative.In contrast, the increasing size of the N9-bonded alkyl groups appears to reduce the negative entropy contribution and thus stabilize the associated complexes.These findings are discussed in terms of dipole-induced-dipole interactions and hydrophobic bonding.
