182067-91-0

Upstream product

• 112914-13-3 2-aminomethyl-4-(4-fluoro-benzyl) morpholine 
• 501-53-1 benzyl chloroformate 
• 22116-33-2 2-(4-fluoro-benzyl-amino)-ethanol 

Downstream Products

• 1027585-31-4 2-(Benzyloxycarbonylamino-methyl)-morpholine-4-carboxylic acid 1-chloro-ethyl ester 
• 182068-00-4 N-(4-Acetyl-morpholin-2-ylmethyl)-2-ethoxy-3-hydroxy-4-nitro-benzamide 
• 182067-93-2 (4-Acetyl-morpholin-2-ylmethyl)-carbamic acid benzyl ester 
• 182067-97-6 1‐[2‐(aminomethyl)morpholin‐4‐yl]ethan‐1‐one 

Relevant academic research and scientific papers

AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Disclosed is a compound having a strong affinity to serotonin-4 receptors, which is useful as an enterokinesis-promoting agent or a digestive tract function-improving agent. Specifically, disclosed is a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. Also specifically disclosed is a pharmaceutical composition containing a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. [In Formula (1), Ar represents a group represented by Formula (Ar-1) or Formula (Ar-2).]

Synthesis and biological activity of 4-amino-5-chloro-2-ethoxy-3- hydroxybenzamides, metabolites of a new gastroprokinetic agent, mosapride

To confirm the proposed structures of the minor metabolites of a potential gastroprokinetic agent, mosapride, 4-amino-5-chloro-2-ethoxy-3- hydroxy-N-(2-morpholinylmethyl)benzamide (3) and the N-(5-oxo-2- morpholinyl)methyl analogue 4 were prepared. As the