182068-59-3

Upstream product

• 182068-51-5 C₂₃H₂₆N₂O₇ 
• 154083-67-7 N-Boc-O-(4-methoxybenzyl)hydroxylamine 
• 824-94-2 p-methoxybenzyl chloride 
• 2014-61-1 N-(4-methoxybenzyloxy)phthalimide 
• 182068-57-1 N-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yloxy)-ethyl]-N-(4-methoxy-benzyloxy)-acetamide 

Downstream Products

• 182068-65-1 (6R,7R)-7-{2-{(Z)-2-[Acetyl-(4-methoxy-benzyloxy)-amino]-ethoxyimino}-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-3-chloromethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-methoxy-benzyl ester 
• 941286-37-9 (Z)-3-acetyl-1-(4-methoxyphenyl)-8-(2-(tritylamino)thiazol-4-yl)-2,6-dioxa-3,7-diazanon-7-en-9-oic acid 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of cephalosporins having hydroxamic acid at C-7 position

The synthesis and in vitro activity of cephalosporins with hydroxamic acid at the 7-position are described. Anti-pseudomonal activity of the compound 11a was shown to be comparable to that of ceftazidime. Especially, the compound 11a exhibited good activity against Gram-positive bacteria including Streptococcus pneumoniae and Staphylococcus aureus.