182140-95-0Relevant academic research and scientific papers
Synthesis of new bifluorophoric probes adapted to studies of donor-donor electronic energy transfer in lipid systems
Grechishnikova, Irina V.,Johansson, Lennart B.-A,Molotkovsky, Julian G.
, p. 87 - 98 (1996)
A series of bifluorophoric fluorescent probes with identical pairs of chromophores have been synthesized. The fluorophores are 9-anthryl, 3-perylenyl and rhodamine 101, and they are separated by a long rigid (bisteroid) or flexible (dotriacontane) diol sp
Mitochondria fluorescent probe with double fluorescence emission as well as preparation method and application thereof
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Paragraph 0021, (2017/05/12)
The invention discloses a mitochondria fluorescent probe as well as a preparation method and application thereof, belonging to the field of functional materials. The mitochondria fluorescent probe has a double fluorescence emission function and is a quaternary phosphonate compound with a structural formula shown by formula I. In the formula I, R is alkyl or aryl, and the anion X is halogen ion. The fluorescent probe disclosed by the invention has very efficient mitochondria specificity recognition ability, and the fluorescent probe molecule presents a double fluorescence emission phenomenon under the excitation of different lights so as to realize precise double fluorescence labeling of mitochondria. In the invention, the fluorescent probe molecule also has excellent light stability, experiences relatively little influence of the charge change on the mitochondria surface, and can realize real-time tracking of the mitochondria distribution and form in a living cell. Moreover, the mitochondria fluorescent probe disclosed by the invention has the advantages of high water solubility, simple synthesis path, simple after-treatment, batch production, relatively low cost and the like and shows a broad market prospect.
