182159-21-3

Upstream product

• 1013-88-3 Benzophenone imine 
• 10406-25-4 4-aminobenzyl cyanide 
• 17201-43-3 4-cyanobenzyl bromide 
• 1204177-18-3 4-nitrobenzyl 2-(4-cyanobenzylideneamino)-2,2-diphenylacetate 
• 3375-31-3 palladium diacetate 
• 1204177-13-8 4-(trifluoromethyl)benzyl 2-(4-cyanobenzylideneamino)-2,2-diphenylacetate 

Relevant academic research and scientific papers

Palladium-catalyzed decarboxylative benzylation of diphenylglycinate lmines

(Figure presented) General reaction conditions for the Pd-catalyzed decarboxylative benzylation of benzyl diphenylglycinate lmines are described. The overall procedure requires a simple catalyst/ligand combination to form a new Csp3-Csp3 bond. Microwave Irradiation greatly accelerated the transformation. Moreover, various heteroaromatlc moieties are tolerated in both the imine and ester components.

Thrombin inhibitors, the preparation and use thereof

Compounds of the formula and the salts thereof with physiologically tolerated acids and the stereoisomers thereof, in which the substituents have the meanings stated in the description, are described. Also disclosed are intermediates for their preparation. The compounds are suitable for controlling diseases.