182247-81-0Relevant academic research and scientific papers
A powerful hydrogen-bond-donating organocatalyst for the enantioselective intramolecular oxa-michael reaction of α,β-unsaturated amides and esters
Kobayashi, Yusuke,Taniguchi, Yamato,Hayama, Noboru,Inokuma, Tsubasa,Takemoto, Yoshiji
, p. 11114 - 11118 (2013/10/22)
Tuning the organocatalyst: An unprecedented enantioselective intramolecular oxa-Michael reaction of unactivated α,β-unsaturated amides and esters catalyzed by a powerful hydrogen-bond-donating organocatalyst has been developed. Furthermore, the products obtained from this reaction have been used for the straightforward asymmetric synthesis of several natural products and biologically important compounds. Copyright
N-substituted-7-amino-5-hydroxy-3-oxoheptanoic acid derivatives and method for producing the same
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, (2008/06/13)
Compounds represented by the following general structural formula (1) and methods for producing the compounds: STR1 R1 represents a group such as benzyloxycarbonyl, R2 represents a lower alkyl group, R3 represents a hydrogen atom or a protecting group, each of M1 and M2 represents a metal atom, and n represents the atomic valence of M1. Intermediates for HMG-CoA reductase inhibitors can be prepared safely and easily from these compounds.
