182250-68-6

Basic information

• Product Name: 3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER
• Synonyms: METHYL 3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOATE;3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER;3,5 Bis(tert-butyldiphenylsilyloxy)benzoic acid methyl ether;Bisbutyldiphenylsilyloxybenzoicacidmethylester;Ca.20%intoluene;3,5Bis(tert-butyldiphenylsilyloxy)benzoicacidmethylether20%intoluene;3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER (CA. 20% IN TOLUENE);Methyl 3,5-Bis(tert-butyldiphenylsilyloxy)benzoate (ca. 20% in Toluene, ca. 0.28mol/L)
• CAS NO: 182250-68-6
• Molecular Formula: C₄₀H₄₄O₄Si₂
• Molecular Weight: 644.95
• Product Categories: Building Blocks for Dendrimers;Functional Materials;Monoalkoxysilanes;Si (Classes of Silicon Compounds);Si-O Compounds
• Mol File: 182250-68-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Refractive Index: 1.593
• CAS DataBase Reference: 3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER(182250-68-6)
• EPA Substance Registry System: 3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER(182250-68-6)

Safety Data

• RIDADR: UN 1993 3/PG II
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 182250-68-6(Hazardous Substances Data)

Usage

General Description

3,5-Bis(tert-butyldiphenylsilyloxy)benzoic acid methyl ester is a chemical compound that is commonly used in organic synthesis and research. It is a derivative of benzoic acid with two tert-butyldiphenylsilyloxy groups attached to the 3 and 5 positions. 3,5-BIS(TERT-BUTYLDIPHENYLSILYLOXY)BENZOIC ACID METHYL ESTER is often utilized as a reagent in the protection and deprotection of hydroxyl groups in organic molecules. It is also used in the synthesis of various biologically active compounds and pharmaceuticals. Additionally, it can serve as a building block for the creation of more complex organic molecules. Overall, 3,5-Bis(tert-butyldiphenylsilyloxy)benzoic acid methyl ester is a versatile and important chemical in the field of organic chemistry.

InChI:InChI=1/C40H44O4Si2/c1-39(2,3)45(34-20-12-8-13-21-34,35-22-14-9-15-23-35)43-32-28-31(38(41)42-7)29-33(30-32)44-46(40(4,5)6,36-24-16-10-17-25-36)37-26-18-11-19-27-37/h8-30H,1-7H3

Upstream product

• 99-10-5 3,5-Dihydroxybenzoic acid 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 150551-00-1 3,5-bis(3,5-bis(4-methoxycarbonylphenyl)benzyloxy)benzyl alcohol 
• 182250-70-0 3,5-di-(tert-butyl(diphenyl)silyloxy)benzyl alcohol 

Relevant articles and documents

Synthesis of Benzo[ b]furans by Intramolecular C-O Bond Formation Using Iron and Copper Catalysis

One-pot processes for the synthesis of benzo[b]furans from 1-aryl- or 1-alkylketones using nonprecious transition metal catalysts have been developed. Regioselective iron(III)-catalyzed halogenation of the aryl ring, followed by iron- or copper-catalyzed O-arylation allowed the synthesis of various structural analogues, including the benzo[b]furan-derived natural products corsifuran C, moracin F, and caleprunin B.

Alternative convergent and accelerated double-stage convergent approaches towards functionalized dendritic polyethers

Alternative convergent synthesis strategies for the preparation of dendritic macromolecules, using either mesylate activation or the Mitsunobu reaction, are described. The synthesis can be further accelerated by using a double stage convergent approach. T