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18226-11-4

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18226-11-4 Usage

Description

N-(2-hydroxyethyl)-2-nitrobenzenesulfonamide, a chemical compound with the molecular formula C8H10N2O5S, is a derivative of sulfanilamide and is commonly used in the pharmaceutical industry as a sulfa drug. It possesses antibacterial properties and is known for its ability to inhibit bacterial growth by interfering with the synthesis of essential molecules.

Uses

Used in Pharmaceutical Industry:
N-(2-hydroxyethyl)-2-nitrobenzenesulfonamide is used as a sulfa drug for its antibacterial properties, specifically targeting the synthesis of essential molecules in bacteria. It is often used in combination with other drugs to treat various bacterial infections.
Used in Chemical Synthesis:
N-(2-hydroxyethyl)-2-nitrobenzenesulfonamide serves as a chemical intermediate in the synthesis of other organic compounds, contributing to the development of new pharmaceuticals and chemical products.
Used in Dyes and Pigments Production:
In the production of dyes and pigments, N-(2-hydroxyethyl)-2-nitrobenzenesulfonamide is utilized as a chemical intermediate, playing a crucial role in the creation of various colorants for different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 18226-11-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,2 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18226-11:
(7*1)+(6*8)+(5*2)+(4*2)+(3*6)+(2*1)+(1*1)=94
94 % 10 = 4
So 18226-11-4 is a valid CAS Registry Number.

18226-11-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2-Hydroxyethyl)-2-nitrobenzenesulfonamide

1.2 Other means of identification

Product number -
Other names N-(2-hydroxyethyl)-nitrobenzenesulfonamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18226-11-4 SDS

18226-11-4Relevant articles and documents

MACROCYCLIC AMIDES ACTING AS PLASMEPSIN INHBITORS FOR THE TREATMENT OF MALARIA

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Paragraph 076-077; 078, (2021/06/26)

The present invention relates to medicine and in particular to the treatment of malarial infections, more particularly to inhibitors of malarial aspartic proteases - plasmepsins. Even more particularly, the invention relates to macrocyclic amides and pharmaceutical compositions thereof and their use as inhibitors for plasmepsins (Plm).

Carbazole compounds and therapeutic uses of the compounds

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, (2015/09/28)

Compounds of the general structural formula (I) and (II) and use of the compounds and salts and hydrates thereof, as therapeutic agents are disclosed. Treatable diseases and conditions include cancers, inflammatory diseases and conditions, and immunodeficiency diseases. (I), (II).

A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds

James, Thomas,Maclellan, Paul,Burslem, George M.,Simpson, Iain,Grant, J. Andrew,Warriner, Stuart,Sridharan, Visuvanathar,Nelson, Adam

supporting information, p. 2584 - 2591 (2014/04/17)

Piperazines are found widely in commercially-available compounds and bioactive molecules (including many drugs). However, in the vast majority of these molecules, the piperazine ring is isolated (i.e. not fused to another ring) and is not substituted on any of its carbon atoms. A modular synthetic approach is described in which combinations of cyclic sulfamidate and hydroxy sulfonamide building blocks may be converted into piperazines and related 1,4-diazepine and 1,5-diazocane scaffolds. By variation of the combinations of building blocks used, it was possible to vary the ring size, substitution and configuration of the resulting heterocyclic scaffolds. The approach was exemplified in the synthesis of a range of heterocyclic scaffolds that, on decoration, would target lead-like chemical space. It was demonstrated that lead-like small molecules based on these scaffolds would likely complement those found in large compound collections. This journal is the Partner Organisations 2014.

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