18227-41-3

Basic information

• Product Name: 5-N-PROPYLHYDANTOIN
• Synonyms: 5-N-PROPYLHYDANTOIN;5-N-PROPYLHYDANTION;5-N-PROPYLHYDANTOIN 98+%;5-Propylhydantoin;5-Propyl-2,4-imidazolidinedione
• CAS NO: 18227-41-3
• Molecular Formula: C6H10N2O2
• Molecular Weight: 142.16
• Mol File: 18227-41-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 137 °C
• Appearance: /
• Density: 1.111g/cm³
• Refractive Index: 1.455
• Storage Temp.: 4°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 8.91±0.10(Predicted)
• CAS DataBase Reference: 5-N-PROPYLHYDANTOIN(CAS DataBase Reference)
• NIST Chemistry Reference: 5-N-PROPYLHYDANTOIN(18227-41-3)
• EPA Substance Registry System: 5-N-PROPYLHYDANTOIN(18227-41-3)

Safety Data

• Hazardous Substances Data: 18227-41-3(Hazardous Substances Data)

Usage

General Description

5-N-PROPYLHYDANTOIN is a chemical compound with the molecular formula C6H11NO2. It is a derivative of hydantoin and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 5-N-PROPYLHYDANTOIN is also used as an antioxidant in rubber and plastics, as well as a stabilizer in pharmaceutical formulations. It is known for its ability to act as a scavenger for peroxides and other reactive oxygen species, making it a valuable compound for the preservation of various materials. Additionally, 5-N-PROPYLHYDANTOIN has been studied for its potential use in the treatment of neurological disorders and as an anticonvulsant agent.

InChI:InChI=1/C6H10N2O2/c1-2-3-4-5(9)8-6(10)7-4/h4H,2-3H2,1H3,(H2,7,8,9,10)

Upstream product

• 506-87-6 ammonium carbonate 
• 111013-52-6 2-aminopentanenitrile monohydrochloride 
• 123-72-8 butyraldehyde 

Relevant articles and documents

Method for preparing 5-substituted chiral hydantoin

The invention discloses a method for directly preparing a 5-substituted chiral hydantoin compound by asymmetric catalyzing and hydrogenating of hydantoin-derived exocycloolefin. A chemical structural formula of the 5-substituted chiral hydantoin compound is expressed by a formula (I) shown in the description. A chemical reaction equation is shown in the description, wherein a compound (II) is the hydantoin-derived exocycloolefin; a compound (III) is a catalyst, and the catalyst is a metal compound of chiral diphosphine ligand. Compared with the prior art, the method has the characteristics that the chiral multiplication is realized, the efficiency and selectivity are high, the atom economy is realized, the green and non-pollution effects are realized, the industrialization is easy, and the like.

Preparation of α-aminothioamides from aldehydes

The conversion of aldehydes into α-aminonitriles and thence into imidazolidin-4-thiones has been studied.Hydrolysis of the appropriate imidazolidin-4-thiones gave thioamides of nine naturally occuring α-amino acids.The possible pre-biotic significance of these compounds is discussed.