182277-07-2Relevant academic research and scientific papers
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics via azido reductive cyclization with HMDST
Kamal, Ahmed,Reddy, B.S. Praveen,Reddy, B.S. Narayan
, p. 6803 - 6806 (1996)
A new facile synthesis of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) ring system has been achieved by reductive cyclization of the azide employing hexamethyldisilathiane (HMDST). The parent unsubstituted PBD and the natural product DC-81 have also been prepared in good overall yields.
